(R)-3-Hydroxypyrrolidine
- Product Name
- (R)-3-Hydroxypyrrolidine
- CAS No.
- 2799-21-5
- Chemical Name
- (R)-3-Hydroxypyrrolidine
- Synonyms
- (R)-PYRROLIDIN-3-OL;(3R)-Pyrrolidin-3-ol;R-HP;98%，ee99%;(R)-3-PYRROLIDINOL;(-)-3-Pyrrolidinol;(3R)-3-PYRROLIDINOL;3-PYRROLIDINOL, (R);(R)-Pyrrolidine-3-ol;R-(-)-3-PYRROLIDINOL
- CBNumber
- CB7494161
- Molecular Formula
- C4H9NO
- Formula Weight
- 87.12
- MOL File
- 2799-21-5.mol
(R)-3-Hydroxypyrrolidine Property
- Melting point:
- 15°C
- Boiling point:
- 215-216 °C (lit.)
- alpha
- 6.5 º (c=3.5% in MeOH)
- Density
- 1.078 g/mL at 20 °C (lit.)
- refractive index
- n20/D 1.488(lit.)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Viscous Liquid
- pka
- 14.91±0.20(Predicted)
- Specific Gravity
- 1.048
- color
- Clear yellow to orange-brown
- optical activity
- [α]20/D +6.5°, c = 3.5 in methanol
- Water Solubility
- Soluble in water and methanol.
- Sensitive
- Air Sensitive & Hygroscopic
- BRN
- 5376132
- CAS DataBase Reference
- 2799-21-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 382981
- Product name
- (R)-3-Pyrrolidinol
- Purity
- 98%
- Packaging
- 1g
- Price
- $85.4
- Updated
- 2023/01/07
- Product number
- 382981
- Product name
- (R)-3-Pyrrolidinol
- Purity
- 98%
- Packaging
- 5g
- Price
- $137
- Updated
- 2023/01/07
- Product number
- P1608
- Product name
- (R)-3-Pyrrolidinol
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $50
- Updated
- 2024/03/01
- Product number
- P1608
- Product name
- (R)-3-Pyrrolidinol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $151
- Updated
- 2024/03/01
- Product number
- L19499
- Product name
- (R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99%
- Packaging
- 1g
- Price
- $61.65
- Updated
- 2024/03/01
(R)-3-Hydroxypyrrolidine Chemical Properties,Usage,Production
Chemical Properties
clear yellow to orange-brown viscous liquid
Uses
(R)-Pyrrolidin-3-ol is used in preparation of allosteric BCR-ABL bifunctional proteolysis targeting chimera compounds.
Purification Methods
The (±)-isomer is purified by repeated distillation ( b 102-104o/12mm, 108-110o/18mm), and the (±)-picrate crystallises from EtOH with m 140-141o. The R(+)-enantiomer has b 70o/0.6mm and [] D +5.6o (c 3.63, MeOH). Its hydrochloride has a negative rotation and its dimethiodide has m 230o and [] 24 -8.02o. [Suyama & Kanno Yakugaku Zasshi (J Pharm Soc Japan) 85 531 1965, Uno et al. J Heterocycl Chem 24 1025 1987, Flanagan & Joullie Heterocycles 26 2247 1987, Beilstein 21 III/IV 44.]
(R)-3-Hydroxypyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-3-Hydroxypyrrolidine Suppliers
View Lastest Price from (R)-3-Hydroxypyrrolidine manufacturers
- Product
- (R)-3-Hydroxypyrrolidine 2799-21-5
- Price
- US $34.00-1.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- (R)-3-Hydroxypyrrolidine 2799-21-5
- Price
- US $80.00-800.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-11-08
- Product
- (R)-3-Hydroxypyrrolidine 2799-21-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2023-03-28